Elementwise approach for simulating transcranial MRI-guided focused ultrasound thermal ablation
نویسندگان
چکیده
منابع مشابه
PET and MRI-guided focused ultrasound surgery for hypoxic-tissue ablation combined with radiotherapy in solid tumors
Background: The rationale was to develop an ablation approach to destroy regions of tumor resistant to radiation and thus reduce the time required for whole tumor ablation, while improving overall tumor control after radiotherapy. Materials and Methods: The system is composed of a micro positron emission tomography (mPET), 7T magnetic resonance imaging (MRI), and a customized MRI-compatible foc...
متن کاملSpatially-segmented undersampled MRI temperature reconstruction for transcranial MR-guided focused ultrasound
BACKGROUND Volumetric thermometry with fine spatiotemporal resolution is desirable to monitor MR-guided focused ultrasound (MRgFUS) procedures in the brain, but requires some form of accelerated imaging. Accelerated MR temperature imaging methods have been developed that undersample k-space and leverage signal correlations over time to suppress the resulting undersampling artifacts. However, in...
متن کاملpet and mri-guided focused ultrasound surgery for hypoxic-tissue ablation combined with radiotherapy in solid tumors
background: the rationale was to develop an ablation approach to destroy regions of tumor resistant to radiation and thus reduce the time required for whole tumor ablation, while improving overall tumor control after radiotherapy. materials and methods: the system is composed of a micro positron emission tomography (mpet), 7t magnetic resonance imaging (mri), and a customized mri-compatible foc...
متن کاملMRI-guided disruption of the blood-brain barrier using transcranial focused ultrasound in a rat model.
Focused ultrasound (FUS) disruption of the blood-brain barrier (BBB) is an increasingly investigated technique for circumventing the BBB(1-5). The BBB is a significant obstacle to pharmaceutical treatments of brain disorders as it limits the passage of molecules from the vasculature into the brain tissue to molecules less than approximately 500 Da in size(6). FUS induced BBB disruption (BBBD) i...
متن کاملPreclinical evaluation of a low-frequency transcranial MRI-guided focused ultrasound system in a primate model.
This study investigated thermal ablation and skull-induced heating with a 230 kHz transcranial MRI-guided focused ultrasound (TcMRgFUS) system in nonhuman primates. We evaluated real-time acoustic feedback and aimed to understand whether cavitation contributed to the heating and the lesion formation. In four macaques, we sonicated thalamic targets at acoustic powers of 34-560 W (896-7590 J). Ti...
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ژورنال
عنوان ژورنال: Physical Review Research
سال: 2019
ISSN: 2643-1564
DOI: 10.1103/physrevresearch.1.033205